This presentation summarizes recent research on estimating the mechanical loading environment of spent nuclear fuel (SNF) during normal storage and transportation scenarios sponsored by the US Department of Energy Spent Fuel and Waste Science and Technology (SFWST) program. Normal conditions of truck, ship, and railroad transportation of SNF were studied with testing and numerical modeling to determine that the shock and vibration loads applied to SNF during transportation are not expected to challenge SNF cladding integrity or the fatigue life of cladding. The 30 cm package drop scenario was studied with experiments and modeling to determine that mechanical loads during a 30 cm SNF package drop scenario are only expected to challenge SNF cladding integrity under worstcase conditions at elevated temperatures. The SFWST program is currently preparing seismic shake table testing to record SNF mechanical loads in a dry storage earthquake scenario. This presentation summarizes the findings of the transportation and package drop research and details the progress made on the current seismic test.