Yam is an important tuber crop nutritionally, socio-culturally, and an income generator for many Nigerian. This explains its high demand both locally and internationally, causing increased production as Nigeria leads world production with about 45.41 million metric tons annually. The peculiarity of yam production in Nigeria entails lower yield, high cost of production, and post-harvest losses. Yam produced in Nigeria falls far below the potential crop yield, therefore, it is essential to close these yield gaps through the provision of solutions to the different constraints that hamper sustainable yam production. Despite the challenges, there is still insufficient information on the impact of policies, weeds, pests, and diseases which constitute major constraints. Nigerian farmers mostly utilize indigenous cultural approaches to manage yam production. Their goal of production is to produce yam cultivars that are suitable mainly for food products leading to the neglect of other cultivars. Few selected institutions with a yam mandate have been working on improving the production of D. rotundata and D. alata through breeding yam cultivars suitable for consumption and resilient against pests and diseases. However, more extensive studies should focus on breeding programs for yam resilient under drought and flooding, with peculiar physicochemical properties that give unique textual qualities considered in pounded yam and other yam food products. In this review paper, the significance and limitations of yam production in Nigeria and her efforts to achieve sustainable production are extensively studied.