Patients referred to the Veterinary Medical Center at Chungbuk National University were analyzed. This study aimed to provide information to clinicians in Korea on the factors affecting fracture incidence in patients adapted to Korean companion animal culture. Eighty cases showing- bone fractures were investigated from January, 2005 to De- cember, 2011. Fractures were mainly observed in miniature dogs such as Yorkshire terrier (12%), Poodle (12%), and Maltese (9%). Almost 50% of all cases were less than 1 year old. Total bone fractures in summer and fall constituted 62%. Fracture incidence was higher in male dogs (54%) than female dogs (46%). Hindlimb fracture (37%) was the most common. Distribution of limb fractures was higher in the femur (19), followed by the tibia/fibula (15), radius/ulna (13), humerus (11), and mandible (8). Pelvic fracture was observed in 19 cases. Simple fracture (84%) was the most common fracture type, followed by comminuted fracture (16%). Distal portion was the most common fracture site in long bones (67%), followed by middle (26%) and proxi- mal bones (7%). Fractures were mainly caused by traffic accidents (43%), whereas 28.5% of fractures were due to falling down. Plate & screw (26%) was the most common method of fracture repair, followed by intramedullary pin (24%), wire (11%), external skeletal fixation (10%), screw (9%), amputation (7%), cross pin (6%), IM pin and wire (5%), and rush pin (1%). Among 80 patients, 79%of pa- tients showed a good prognosis after surgery, whereas 13% patients did not experience a good result. This study shows that miniature dogs are prone to falling and fractures, espe- cially in the distal part of long bones.

다능성 세포를 포함하는 골막은 골모세포와 연골세포로 분화될 수 있다. 그리고 배양된 골막유래세포는 골형성 능 력을 가지고 있다. 이 연구의 목적은 골막유래 세포들과 골이식재 간의 상호작용을 평가하는 것이다. Sprague-Dawley 랫드의 두개골 골막에서 세포를 분리한 다음, 배양된 골막유래세포를 beta-tricalcium phosphate (β-TCP)와 함께 임계결손부 크기의 두개결손부에 이식하였다. 모든 랫드는 골이식 수술 후 8주째에 희생되었으며, 골이식부의 골형성 능력은 일반방사선, micro CT 및 조직검사를 통해 평가되었다. β-TCP와 함께 이식된 골막유래세 포는 골결손부에서 더욱 증가된 석회화작용을 나타내었으며, 골결손부 안쪽 및 가장자리에 골밀도 증가와 신생골이 형 성되었다. 특히 골막유래세포는 β-TCP만 단독으로 이식하였을때보다 함께 이식 시 효과적으로 신생골을 형성하였다. 이러한 결과는 배양된 골막유래세포가 골결손부에서 골형성을 증진시킬 수 있는 가능성을 보였다.