We determined intravitreal levels of vascular endothelial growth factor (VEGF) and pigment epithelium derived factor (PEDF) in patients with early phase rhegmatogenous retinal detachment (RRD). Twenty five eyes of 25 RRD patients with symptom onset from one day to 21 days prior to vitrectomy were selected. Concentrations of VEGF and PEDF in vitreous were determined by enzyme-linked immunosorbent assay and relationships between these concentrations and durations and involved quadrants were analyzed. Duration of RRD was found to show significant correlation with PEDF concentration. However, number of involved quadrants did not show correlation with PEDF concentration in vitreous.

We evaluated the surgical results of vitrectomy for macular hole, according to the type of gas. Retrospective analysis was performed on the clinical data of 45 patients who underwent macular hole surgery without any complication influencing visual acuity who were included in this study. They were divided into two groups according to the type of gas: Group 1 - SF6, Group 2 - C3F8. We compared the anatomical results of these groups. This study shows that the type of gas does not significantly influence surgical results. However, large sized macular holes lead to poor post-operative visual acuity.