To safely dispose of highly radioactive spent resin and concentrate waste generated through nuclear power plant operations, it is essential to meet the physicochemical properties requirements of the packages and ensure the accuracy and reliability of radiological characteristics determination. Both spent resin and concentrate are packaged in high-integrity containers (HICs) after drying and are homogeneous waste products generated in the primary system and liquid radioactive waste treatment system. Meeting the physicochemical properties requirements does not appear to be difficult. However, to achieve reliable radiological characterization of high-integrity container packages, it is necessary to take a representative sample and perform accurate radiological analysis. Therefore, this paper discusses the methodology for evaluating the radionuclide inventory of high radioactive resin and concentrate packages, as well as the essential element technology and considerations. For relatively high radioactive resin and concentrate packages, the radionuclide inventory for each package should be evaluated with high reliability through direct radiological analysis of the representative samples collected for each package. This can contribute to the efficient operation of radioactive waste disposal facilities. Radionuclide-specific concentrations directly analyzed for each package will be managed in a database. As analytical data accumulates and direct measurements of high-integrity container package such as the radwaste drum assay system (RAS) become feasible, statistical techniques such as correlation analysis between easy-tomeasure (ETM) nuclides and difficult-to-measure (DTM) nuclides can lead to the development of efficient and reasonable indirect evaluation methods, such as scaling factor and the mean activity concentration method. As for the element technology, a remote representative sampling technique should be developed to safely and effectively take representative samples of highly radioactive materials, including granulated or hardened concentrate waste. Considerations should also be given to determining the sample quantity representing each package, as well as establishing radiation calibration and measurement methods appropriate to the radiation levels of the representative samples.