With the rapid improvement of hardware and software-related IT technology, applying A.I. to the private and public sectors, such as the Food Poisoning Prevention Program in Nevada and Smart City based on big data in Boston, is steadily increasing. However, the cases of application to the regulation sector of government are still insufficient. The Korea Institute of Nonproliferation and Control (KINAC) is studying to apply A.I. technology to the regulation to improve the objectivity, consistency, and efficiency of classification and export licensing review. The KINAC developed the Nation Nuclear Technology Information Collection and Analysis System using A.I. techniques such as machine learning and deep learning techniques. KINAC and FNC Technology are developing the Export Risk Assessment System using A.I. modules and Bayesian Networks. The KINAC and Korea Atomic Energy Research Institute (KAERI) are developing an inventory history management system subject to the Nuclear Cooperation Agreements. The Nuclear Safety and Security Commission (NSSC) and KINAC operate the Nuclear Import and Export Control System (NEPS) for application and export license review according to relevant laws such as the Foreign Trade Act. Therefore, preparing an integration plan for the existing NEPS and the new systems is necessary. Since the NEPS has to be operated and accessible at all times, so the stability of the NEPS is the most important when integration and linking. So, it is suggested that the Collection and Analysis System and the Risk Assessment System, which require a lot of data traffic, are configured in a server separate from the NEPS, and the new DB and the NEPS DB are only linked. An inventory history management system is also suggested to be integrated and configured into the NEPS. Third, it is recommended that each system lists the information provided to or received from the NEPS in advance, and one-way communication should be performed basically. Two-way communication should be performed when necessary. Finally, against various cyber accidents and information leakage, it is proposed to review security vulnerabilities and apply essential security measures and guidelines. Through the integration and linkage of these systems, it is expected that the objectivity, consistency, and efficiency of classification and export licensing review of the KINAC are strengthened, and national transparency of development, production, and use of nuclear material is enhanced. It can be satisfied with the increasingly strengthened demands of the international community on duty for strategic item management.