The aim of this study was to evaluate the efficacy of the Optiscope video system for anesthesia. Intubation was successful in all 60 patients. The first attempt success rate was 85%. The median time (IQR) [range] to intubation was 20 sec (14-43) [8- 420]. Seven patients required two attempts and in two patients, intubation of the trachea was achieved on a third attempt. The Optiscope video system is an effective and safe device for use in endotracheal intubation in adult patients with normal airways. Conduct of further clinical studies will be necessary to evaluate its role in patients with anticipated difficult airways.