Yang Shen (1488-1559) was born in Si Chuan Xin Dou. 《Ming Shi》 said that Yang Shen is the most famous for the extensive memorization and abundant writings. Yang Shen also contributed to the philology researches. According to Wang Wen Cai’s 《Yang Shen Xue Pu》, Yang Shen had many kinds of writings, such as 《Shuo Wen Xian Xun》, 《Liu Shu Lian Zheng》, 《Liu Shu Bo Zheng》 etc., but most of them are disappeared. 《Liu Shu Suo Yin》was thought that it’s disappeared, it can be found in the library of RENMIN UNIVERSITY of CHINA. It was included in 《Si Ku Quan Shu Cun Mu Cong Shu》. From Yang Shen’s 《Liu Shu Suo Yin-Introduction》, we knows that Yang Shen was based on abundant philology researches to appear his research system. Yang Shen had different academic judgements for each text researchers’s theories to appear Yang Shen’s conceptions of “Zhuan Zhu Gu Yin”. 《Qin Ding Si Ku Quan Shu Zong Mu》 was based on the the text textual content to comment Yang Shen’s 《Liu Shu Suo Yin》 negative. We can discuss the comment is appropriate or not? 《Liu Shu Suo Yin》 is distinguished into rhyme, so it had its own system. These researches are related to Yang Shen’s other research works in Xiao Xue. In philology researches, we can investigate Yang Shen’s contribution to philology researches with 《Liu Shu Suo Yin》 to clarify and analyze.