Google Trends is a useful tool not only for setting search periods, but also for providing search volume to specific countries, regions, and cities. Extant research showed that the big data from Google Trends could be used for an on-line market analysis of opinion sensitive products instead of an on-site survey. This study investigated the market share of tumor necrosis factor-alpha (TNF-α) inhibitor, which is in a great demand pharmaceutical product, based on big data analysis provided by Google Trends. In this case study, the consumer interest data from Google Trends were compared to the actual product sales of Top 3 TNF-α inhibitors (Enbrel, Remicade, and Humira). A correlation analysis and relative gap were analyzed by statistical analysis between sales-based market share and interest-based market share. Besides, in the country-specific analysis, three major countries (USA, Germany, and France) were selected for market share analysis for Top 3 TNF-α inhibitors. As a result, significant correlation and similarity were identified by data analysis. In the case of Remicade’s biosimilars, the consumer interest in two biosimilar products (Inflectra and Renflexis) increased after the FDA approval. The analytical data showed that Google Trends is a powerful tool for market share estimation for biosimilars. This study is the first investigation in market share analysis for pharmaceutical products using Google Trends big data, and it shows that global and regional market share analysis and estimation are applicable for the interest-sensitive products.

Our research is aimed at predicting recent trend and leading technology for the future and providing optimal Nano technology trend information by analyzing Nano technology trend. Under recent global market situation, Users’ needs and the technology to meet these needs are changing in real time. At this point, Nano technology also needs measures to reduce cost and enhance efficiency in order not to fall behind the times. Therefore, research like trend analysis which uses search data to satisfy both aspects is required. This research consists of four steps. We collect data and select keywords in step 1, detect trends based on frequency and create visualization in step 2, and perform analysis using data mining in step 3. This research can be used to look for changes of trend from three perspectives. This research conducted analysis on changes of trend in terms of major classification, Nano technology of 30’s, and key words which consist of relevant Nano technology. Second, it is possible to provide real-time information. Trend analysis using search data can provide information depending on the continuously changing market situation due to the real-time information which search data includes. Third, through comparative analysis it is possible to establish a useful corporate policy and strategy by apprehending the trend of the United States which has relatively advanced Nano technology. Therefore, trend analysis using search data like this research can suggest proper direction of policy which respond to market change in a real time, can be used as reference material, and can help reduce cost.