Air quality monitoring networks are very important facilities to manage urban air pollution control and to set up an environmental policy. Since air quality monitoring network of Daegu was allocated from 1980s to mid-90s, there is need to reevaluate it and relocated its site. This study was evaluated the position of Daegu air quality monitoring station by unit environmental sensitivity index, grid emission rate, CAI (Comprehensive Air-quality Index) point. The investigation domain covered an area of 16 × 24 km centered at the metropolitan area of Daegu with grid spacing of 2 km. The location of alternative air quality monitoring networks was selected through optimization and quintiles analysis of total score. The result showed that all things considered, new air quality monitoring network need to install grid numbers 10, 28, 36, 37, 46. We also recommand three scenarios of alternative air quality monitoring network when considering unit environmental sensitivity index, emission rate and CAI point.