The CLASS (Computerized LAyout Solutions using Simulated annealing) deals with the inter-cell and intra-cell layout problems in a cellular manufacturing environment. It focuses on the relative placement of manufacturing cells to minimize the total material flow (cost). The method is based on simulated annealing, which has been successfully applied for solving facility layout problems. This algorithm has a character of the independence of the final solution to the initial solution. There are 2 comparisons were made with applying 2-Opt algorithm to the CLASS when finding initial variables and used 2-Opt algorithm again after finding a solution by using 2-Opt algorithm to the CLASS to accommodate to improve the output.