This study evaluates the analytical performance of a newly developed miniaturized disposable U-tube for an automated blood viscometer and compares it to conventional viscometers. Whole blood viscosity (WBV), essential for circulatory function, exhibits non-Newtonian behavior, posing challenges for measurement at low shear rates. The blood viscometer, based on a scanning capillary tube method, used disposable U-tubes to measure viscosities across a shear rate range of 1s⁻¹ to 1,000s⁻¹. Precision evaluation showed stable coefficients of variation (CV) across different viscosity levels. Repeatability assessment indicated consistent CV values, demonstrating the reliability of the device. The agreement with the LV-III Brookfield viscometer and MCR 92 Rheometer was analyzed using Bland-Altman plots, which revealed minor systematic biases and consistent differences across the measurement range. Correlation analysis using Passing-Bablok regression showed high correlation coefficients (R > 0.96) with regression slopes close to 1. The newly developed miniaturized disposable U-tube exhibits excellent precision, reliable repeatability, and high correlation with established methods, enhancing laboratory productivity and offering potential for clinical applications. Further studies with human blood samples are recommended to confirm its clinical applicability.

이 연구는 최대근력형과 근지구력형 저항운동이 총운동량과 혈액점도 및 적혈구용적률에 미치는 영향을 조사하고자 하였다. 연구대상자는 저항운동 경력 12개월 이상의 20대 남성 15명으로 선정하였으며, 실험 전 벤치프레스 1RM을 측정하였으며, 조건 별 실험은 1주일간의 간격을 두고 교차배분하여 6세트 씩 최대반복수행 하였다. 그 결과 총운동량은 근지구력강도가 최대근력강도에 비해 높게 나타났으며 (p<.001), 혈액점도와 적혈구용적률은 총운동량에 관계없이 운동 전보다 운동 후에 높아졌다(p<.01). 종합 하면 혈액점도는 운동강도와 운동량에 영향을 받지 않으며, 일회성 저항운동으로 증가한다는 것을 알 수 있었다. 이는 저항운동 프로그램을 구성하는데 있어 임상적으로 의의가 있으며 혈관질환에 관련된 임상환 자들의 운동프로그램을 작성하는데 있어 참고자료가 될 수 있을 것으로 판단된다.

The present study investigated the blood flow at microvascular network. The role of the blood viscosity and the yield stress of blood on the flow at the microvascular network was examined to find the condition of hemostasis. When the yield stress was less than 0.005Pa, there was no stagnant region in the capillary network used in the study. However, when the yield stress increased to 0.05Pa, stagnant areas began to appear, which grew and expanded rapidly with further increase in the yield stress. From the blood viscosity profile of a patient, one can estimate the yield stress of blood, from which the risk of hemostasis can be determined.