In the Korean Building Code (KBC), the Design Eccentricity involves the torsional amplification factor (TAF), and the inherent and accidental eccentricities. When a structure of less than 6-stories and assigned to seismic design category C or D is designed using equivalent static analysis method, both KBC-2006 and KBC-2009 use the TAF but apply different calculation methods for the of design eccentricity. The design eccentricity in KBC-2006 is calculated by multiplying the sum of inherent eccentricity and accidental eccentricity at each level by a TAF but that in KBC-2009 is calculated by multiplying only the accidental eccentricity by a TAF. In this paper, the damage indices of a building with planar structural irregularity designed by different design eccentricities are compared and the relationship between the earthquake damage and design eccentricity of the building is evaluated. On the basis of this study, the increment of design eccentricity results in the decrement of final eccentricity and global damage index of structure. It is observed that design eccentricity in KBC-2006 reduces the vulnerability of torsional irregular building compared to design eccentricity in KBC-2009.