Traumatic eosinoph ilic gra nul oma(TEG) of the oral mucosa is considered to be a reactive benign lesion, which commonly ma nifests as an ulcer with eleva ted and indurated borders Clinically. this lesion simulates a maligna nt tumor Hi s to logy shows a diffut;e‘ dense. polymorphic. and eosinophil-rich cellular infiltrate. which extends deeply into the un derl ying soft ti ss ues‘ A major constituent of infïltrates is a population of mitotically active, large. atypical monol1 uclear cell s . Immunohi stologic eval uation of the large atypical cells has suggested a myofibroblastic 0 1' histi ocyti c origi 1γ However ‘ recent reports have shown that these cells are positive for CD30 antigen. We have descr ibed a case of ora l mucosal lesions with featu res of TEG that had a CD68 posite atypical cells. The large cells showed s trong pos itive for CD68‘ but negative for CD30. The sma ll Iymphocy tic cells exprerssed CD3. This case was interpreted as an atypical histiocytic g ran uloma .