Purpose: This study was tried to identify the effects of simulation program by applying hazard perception training on self-efficacy of patient safety, error recovery and problemsolving process in nursing students. Methods: A nonequivalent control group designed was used. The study was composed of hazard perception training and simulation program. Sixteen teams of a total of 61 nursing students participated in the simulation program using a high fidelity simulator. The collected data were analyzed by descriptive statistics, χ2-test and t-test using PASW 18.0 program. Result: There were statistically signigicant in self-efficacy of patient safety(t=2.55, p=.013), error recovery(t=2.82, p=.007), and problem-solving process(t=3.29, p=.002) in the experimental group. Conclusion: These results indicate that the simulation program by applying hazard perception training is effective in improving self-efficacy of patient safety, error recovery and problem-solving process for nursing students. Further study is recommended to confirm the long-term effects of the simulation program by applying hazard perception training.