Malignant mixed tumor is an aggressive malignant neoplasm composed of heterologous malignant epithelial and stromal components. It is a rare neoplasm, accounting for 0.05 % of all salivary gland tumors and 0.16 % of all malignant salivary gland tumors. The tumor may occur in the background of a preexisting pleomorphic adenoma or may arise de novo. We report on an 84-year-old female who was diagnosed with carcinosarcoma on her left parotid gland. Microscopically, the tumor consisted of two components - mainly myxoid chondrosarcoma (75%), poorly differentiated carcinoma and a few remnants of benign pleomorphic adenoma in the periphery of the tumor.

Malignant salivary gland neoplasms constitute approximately 1% to 3% of all head and neck malignancies and only 0.3% of all malignant neoplasms. Malignant mixed tumors represent 2.2% of all salivary gland tumors. We experienced a huge malignant mixed tumor in the parotid gland, and obtained good results after surgical excision of the parotid gland and reconstructive operation. Therefore, we report on our experience and review the articles related to that tumor.