The construction and ability of CAE program are presented. The merit and ability of MATLAB which is widely using in the field of recently engineering and natural science are also introduced. Also, analysis program of frame structure used the MATLAB language which is divide in 4th generation language is presented. In this paper, the proposed program using MATLB language to be based upon the composition of general CAE program is composed to preprocess, solver and post-process procedure. And it is able to carried out the static and eigenvalue analysis of truss structure and two dimensional frame structure. Also, for the sample pre-processing and post-processing, it is used the characteristic of input window and plot window to be made of the various GUI function. Each finite elements to be required for analysis is formulated by the Galerkin's method, as a kind of weighted residual method. For check of the results of calculation for program used in this paper, the results to be calculated using program to be developed by the author was compared with its of ANSYS code for general structural analysis about two dimensional truss and frame structure.