The purpose of this study was to investigate the effect of horticultural therapy program focused on indoor activities for cancer patients on post-traumatic growth and self-integrity. Seven cancer patients were participated. Experimental group of 7 members received a horticultural therapy program. And this study was performed from May 12 to June 30 in 2014. As the results, the sub-category of self integrity was not statistically significant, but total self-integrity level of the experimental group increased significantly after horticulture therapy (p=0.042). Post-traumatic growth level of the experimental group increased after horticulture therapy, but it was not statistically significant. Therefore horticultural therapy program focused on indoor activities could be utilized as an appropriate program for increase of self-integrity in cancer patients in future.