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        검색결과 2

        1.
        2024.03 KCI 등재 구독 인증기관 무료, 개인회원 유료
        Carbon dots (CDs) are a novel type of fluorescent nanoparticles with a particle size smaller than 10 nm. They possess several advantageous properties, including excellent biocompatibility, light stability, water solubility, and low toxicity. CDs have been widely researched in recent years. As a treasure of ancient Chinese science, traditional Chinese medicine (TCM) is rich in various active ingredients and has a variety of pharmacodynamic effects, which have been used for thousands of years. TCM-CDs prepared with TCM as carbon source can create some special functions and then may play a greater medicinal value. The purpose of this review was to engage in an in-depth conversation about the use of TCM-CDs in medical therapy and bioimaging. Firstly, this study provides a comprehensive exploration of different synthesis methods for TCM-CDs, comparing their respective advantages and disadvantages. Subsequently, the intrinsic pharmacological activity of TCMCDs, encompassing antibacterial, hypoglycemic, hemostatic, anticancer, and anti-inflammatory effects, is mainly discussed, alongside their underlying mechanisms of action. Additionally, investigations into in vitro imaging of diverse cell types and the distribution and uptake of TCM-CDs under in vivo imaging guidance are presented. Finally, the significance of TCM-CD research, key challenges and issues within this field, and future directions for development are summarized and outlined.
        5,500원
        2.
        2020.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        ultrafiltration, diafiltr바이오의약품 중에서도 항체의약품의 수요가 증가함에 따라 항체를 상업용으로 개발하기 위한 연구가 활발히 진 행되고 있다. 항체의약품의 제조공정 중 downstream 공정은 의약품 성능에 직접적으로 영향을 미치기 때문에 중요하게 다뤄 지며, 본 총설은 그 중에서도 농축 및 제제화를 목적으로 행해지는 한외여과 및 정용여과 공정에서 사용되는 한외여과막의 주요 제품 및 공정 특성을 살펴보고, 최근 연구 동향에 대해 소개하고자 한다.ation, concentration, formulation, antibody-based therapeutics
        4,300원