There has been a steady rate of accident in Coal Thermal Power Plants which have relatively higher chance of mortality. However, neither the systematic view of safety management nor the methodology such as safety factors or system requirements are yet to be studied in detail. Therefore, this study aims to propose a methodology to preemptively deal with safety issues and to secure fact focused responsibility in safety. It consists of two main parts. First, the Safety Measurement Index(SMI) with total 50 factors is proposed by analyzing the key factors that contribute to safety accidents based on failure mode and effect analysis (FMEA) and quality function deployment (QFD). To analyze the safety requirements, index presented by major countries and organizations are discussed. Second, main features of intelligent CCTV are studied to determine their relative importance for the framework of Smart Safety Management System (SSMS). Main features are discussed with four technological steps. Also, QFD was held to analyze to analyze how key technologies deal with Quality Measurement Index(QMI). The research results of this study reveal that scientific approaches could be utilized in integrating CCTV technologies into a smart safety management system in the era of Industry 4.0. Moreover, this reasearch provides an specific approach or methodology for dealing with safety management in Coal Thermal Power Plant.