The purpose of this study is to examine the effects of some practical teaching and learning methods using multimedia literacy in Japanese language education. As components of multimedia literacy, SNS, YouTube clips, the recording function of mobile phones, and reading tasks were given to 29 university students in an introductory level Japanese language class. At the end of the semester, the students were asked to participate in a survey in which they evaluated whether the teaching and learning methods using multimedia literacy were helpful. The findings of the study were as follows: First, problem-solving skills, and reading and speaking skills were enhanced by using a team-based learning. Second, the class using SNS was very useful for enhancing the language skills due to the convenient presentation of learning materials, the submission and the review of assignments, and the immediate feedback. Third, Korean composition sentences and reading tasks made a great contribution to practicing pronunciation and enhancing conversation skills. Fourth, voice files and YouTube clips provided for absent students could make up for the contents they missed in class. On the basis of this study, a variety of teaching and learning methods using multimedia literacy are expected to be designed and discussed.