만성 위염, 위암, 위궤양 등을 유발하는 Helicobacter pylori는 항생제의 부작용, 내성, 다제 내성균의 등장으로 항생제만으로 안전하게 치료하기는 어려운 실정이다. 안전하게 제균을 하기 위해 항생제를 대체할 수 있는 천연물 소재 치료제를 개발하기 위해 많은 연구들을 하고 있다. 선행 연구를 통해 in vitro 실험 H. pylori 항균 효과 평가를 통해 항균 효과가 우수한 추출물을 알아보고자 한다.
Field research was undertaken for recovering mosquito larval mermithid parasite, Romanomermis species in rice fields in 54 different areas in period of May through October, 2009. Of 54 area rice fields surveyed, Romanomermis sp. recoveries were made from 4 areas. 32 Anopheles mosquito larvae, malaria disease vector were infected and died from samples collected in Pochon area, and a total of 10 Culex mosquito larvae, house frequenting mosquito were infected to death in 3 different areas, Gimpo, Sangju and Gurae, respectively. On the basis of positive natural infection record, an intensive host-parasite occurrences and/or population study was surveyed in foci area of Pochon in small pond (P) and Rice paddies (A and B) during 5 months till end of October. The natural mermithid infection was continuously occurred from June through October in weekly samples, however the rate of infection was appeared higher in June-July, thereafter the rate gradually decreased in progress of the season. The highest natural infection rate was observed from the Pond 9.1% followed by Rice paddy "A" 5.2%, Rice paddy "B" 2.4%, respectively. Including 2 other Rice paddies "C" and "D", a total mosquito larvae collected was 3,270, an overall average natural infection rate was recorded as 3.7% (121 Anopheles mosquito larvae infected).