본 연구는 코로나바이러스 감염증-19(이하 코로나19) 팬데믹 상황에서 간호대학생의 취업불안 에 코로나19에 대한 지식과 두려움이 어떠한 영향을 주는지 확인하기 위해 시도되었다. 본 연구대상자는 간호대학에 재학 중인 1학년에서 4학년까지 157명이었으며, 자료수집은 2021년 12월 9일부터 2022년 2월 21일까지 연구에 동의한 간호대학생을 대상으로 시행하였다. 수집된 자료의 일반적 특성에 따른 취업불안 정도의 차이는 Independent t-test, One-way ANOVA로 분석하였고, 변수 간의 상관관계는 Pearson correlation coefficient로, 간호대학생의 취업불안에 영향을 미치는 요인은 단계적 다중회귀 방법을 사용하 여 통계적으로 분석하였다. 본 연구결과, 연구대상자들의 취업불안은 코로나19에 대한 두려움(r=.386, p<.001)과 유의한 상관관계가 있었으며, 간호대학생의 취업불안을 예측할 수 있는 주요한 요인은 코로나19 에 대한 두려움과 대학 생활 만족도였다. 이상의 결과를 볼 때 코로나19에 의한 간호대학생의 취업불안을 줄이기 위해서 취업을 준비하는 학생들에게 두려움을 줄이고 긍정적 정서를 향상할 수 있는 다양한 프로그 램을 마련할 필요가 있다.

In order to extend the business viability of carbon nanotubes (CNTs), research on CNT dispersion in a solvent as well as in polymer matrix should be established. Herein, three kinds of dispersing agents, sodium deoxycholate (DOC), sodium dodecylbenzene sulfonate (NaDDBS), polyvinyl pyrrolidone (PVP), are selected and applied to quantify the dispersibility and dispersion stability of CNT aqueous dispersion. The dispersibility of CNT dispersion with the PVP, evaluated via viscosity and particle size analyses, are superior to those with the DOC and NaDDBS dispersing agents. CNT aqueous solution dispersed with PVP showed slightly higher viscosity and narrower particle size distribution than those with DOC and NaDDBS dispersing agents. In addition, the dispersion stability of CNT dispersion with the PVP, measured via lumisizer analyses, are superior to those with the DOC and NaDDBS dispersing agents. HR-TEM analysis verifies that the outstanding dispersibility and dispersion stability of CNTs in aqueous solution are due to the effect of the robust polymer wrapping of the PVP dispersing agent on the CNT surface. From the results of this study, the guidelines for the selection of the suitable dispersing agents and the systematic evaluation of dispersibility and dispersion stability of CNT dispersions can be suggested.

A solid-phase competition enzyme-linked immunosorbent assay (ELISA), recombinant VP2 (rVP2) protein, and monoclonal antibody (mAb) were developed for the specific and sensitive detection of porcine parvovirus (PPV) antibodies in pig sera. A total of 1,544 sera samples were collected from breeding pig farms located in the Gyeongsangbuk-do Province in the Republic of Korea. The optimal operating conditions of SC-ELISA were as follows. The concentration of rVP2 proteins coated on the wells was 4 μg/mL, the swine sera were diluted 1:2, and the HRP-conjugated PPV VP2 mAb (9A8 clone) was used at 500 ng/mL. These results suggest that the SC-rVP-ELISA assay may be a valuable alternative to the current diagnostic tools used to detect PPV-specific monoclonal antibodies and broadly monitor PPV infections in domestic pigs at different breeding stages.

Colon cancer has been considered a leading cause of cancer-associated death. Folic acid is a vitamin necessary for cellular physiological functions and cell viability. However, the association between folic acid intake and colon cancer has been examined in several prospective cohort studies are controversial. This study investigated the effects of folate intake on colon carcinogenesis and oxidative stress in an azoxymethane (AOM)/dextran sodium sulfate (DSS) institute for cancer research (ICR) mouse model. Thirty male ICR mice (5 weeks old) were divided into the control group and the experimental group supplied 0.03% folic acid via drinking water (50 mL/week/mouse) for 6 weeks. To induce colonic pre-neoplastic lesions, the animals were subcutaneously injected three times weekly with AOM (10 mg/kg body weight), followed by 2% DSS in drinking water for a week. Folic acid supplementation significantly suppressed the total number of aberrant crypt foci and aberrant crypts. Histological image data showed that folic acid supplementation attenuated neoplastic change. In addition, we measured the thiobarbituric acid reactive substances concentration of dry feces samples to identify the effect of folic acid on reactive oxygen accumulation. The folic acid supplementation group had reduced reactive oxygen species levels in dry feces compared to the control group. In conclusion, these findings indicate that folic acid suppresses colon carcinogenesis and oxidative stress in an AOM/DSS mouse model.

We aimed to predict the Italian ryegrass (IRG) productivity change of introduced and domestic varieties based on climate factors and identify suitable areas for IRG cultivation using the RCP 8.5 scenario. The minimum mean air temperature in January showed the highest correlation with productivity. The ratio of possible and low productivity areas was high in Gangwondo, and the ratio of suitable and best suitable areas was relatively high in the central and southern regions in the past 30 years. The change in the IRG cultivation area was found to be 26.9% in the best suitable area between 1981–2010 but increased significantly to 88.9% between 2090s. In the IRG suitability comparison classes between domestic and introduced cultivars, the ratio of suitable and best suitable areas was relatively high in the domestic varieties during the past 30 years. However, there is almost no difference between the IRG domestic and introduced varieties in the IRG suitability classes after the 2050s. These results can predict changes in the IRG suitability classes between domestic and introduced cultivars according to the climate change scenario, but there are limitations in accurately predicting the productivity of IRG because the results may vary depending on other environmental factors.