This study was aimed to isolate bacterial inoculants producing chitinase and evaluate their application effects on corn silage. Four corn silages were collected from four beef cattle farms to serve as the sources of bacterial inoculants. All isolates were tested against Fusarium graminearum head blight fungus MHGNU F132 to confirm their antifungal effects. The enzyme activities (carboxylesterase and chitinase) were also measured to isolate the bacterial inoculant. Based on the activities of anti-head blight fungus, carboxylesterase, and chitinase, L. buchneri L11-1 and L. paracasei L9-3 were subjected to silage production. Corn forage (cv. Gwangpyeongok) was ensiled into a 10 L mini silo (5 kg) in quadruplication for 90 days. A 2 × 2 factorial design consists of F. graminearum contamination at 1.0104 cfu/g (UCT (no contamination) vs. CT (contamination)) and inoculant application at 2.1 × 105 cfu/g (CON (no inoculant) vs. INO (inoculant)) used in this study. After 90 days of ensiling, the contents of CP, NDF, and ADF increased (p<0.05) by F. graminearum contamination, while IVDMD, acetate, and aerobic stability decreased (p<0.05). Meanwhile, aerobic stability decreased (p<0.05) by inoculant application. There were interaction effects (p<0.05) on IVNDFD, NH3-N, LAB, and yeast, which were highest in UCT-INO, UCT-CON, CT-INO, and CT-CON & INO, respectively. In conclusion, this study found that mold contamination could negatively impact silage quality, but isolated inoculants had limited effects on IVNDFD and yeast.

In general, after the decommissioning of nuclear facilities, buildings on the site can be demolished or reused. The NSSC (Nuclear Safety and Security Commission) Notice No. 2021-11 suggests that when reusing the building on the decommissioning site, a safety assessment should be performed to confirm the effect of residual radioactivity. However, in Korea, there are currently no decommissioning experiences of nuclear power plants, and the experiences of building reuse safety assessment are also insufficient. Therefore, in this study, we analyzed the foreign cases of building reuse safety assessment after decommissioning of nuclear facilities. In this study, we investigated the Yankee Rowe nuclear power plant, Rancho Seco nuclear power plant, and Hematite fuel cycle facility. For each case, the source term, exposure scenario, exposure pathway, input parameter, and building DCGLs were analyzed. In the case of source term, each facility selected 9~26 radionuclides according to the characteristics of facilities. In the case of exposure scenario, building occupancy scenario which individuals occupy in reusing buildings was selected for all cases. Additionally, Rancho Seco also selected building renovation scenario for maintenance of building. All facilities selected 5 exposure pathways, 1) external exposure directly from a source, 2) external exposure by air submersion, 3) external exposure by deposited on the floor and wall, 4) internal exposure by inhalation, and 5) internal exposure by inadvertent ingestion. For the assessment, we used RESRAD-BUILD code for deriving building DCGLs. Input parameters are classified into building parameter, receptor parameter, and source parameter. Building parameter includes compartment height and area, receptor parameter includes indoor occupancy fraction, ingestion rate, and inhalation rate, and source parameter includes source thickness and density. The input parameters were differently selected according to the characteristics of each nuclear facility. Finally, they derived building DCGLs based on the selected source term, exposure scenario, exposure pathway, and input parameters. As a result, it was found that the maximum DCGL was 1.40×108 dpm/100 cm2, 1.30×107 dpm/100 cm2, and 1.41×109 dpm/100 cm2 for Yankee Rowe nuclear power plant, Rancho Seco nuclear power plant, and Hematite fuel cycle facility, respectively. In this study, we investigated the case of building reuse safety assessment after decommissioning of the Yankee Rowe nuclear power Plant, Rancho Seco nuclear power plant, and Hematite fuel cycle facility. Source terms, exposure scenarios, exposure pathways, input parameters, and building DCGLs were analyzed, and they were found to be different depending on the characteristics of the building. This study is expected to be used in the future building reuse safety assessment after decommissioning of domestic nuclear power plants. This work was

The aim of this study was to investigate the effect of isolated lactic acid bacteria (LAB) on the quality of high moisture rye silage. Rye forage (Secale cereale L.) was harvested at the heading stage (27.3% of dry matter (DM)) and cut into approximately 3-5 cm lengths. Then, the forage divided into 4 treatments with different inoculants: 1) No additives (CON); 2) Lactobacillus brevis strain 100D8 at a 1.2 x 105 colony-forming unit (cfu)/g of fresh forage (LBR); 3) Leuconostoc holzapfelii strain 5H4 at a 1.0 x 105 cfu/g of fresh forage (LHO); and 4) Mixture of LBR and LHO (1:1 ratio) applied at a 1.0 x 105 cfu/g of fresh forage (MIX). About 3 kg of forage from each treatment was ensiled into a 20 L mini-bucket silo in quadruplicate for 100 days. After silo opening, silage was collected for analyses of chemical compositions, in vitro nutrient digestibilities, fermentation characteristics, and microbial enumerations. The CON silage had the highest concentrations of neutral detergent fiber and acid detergent fiber (p = 0.006; p = 0.008) and a lowest in vitro DM digestibility (p < 0.001). The pH was highest in CON silage, while lowest in LBR and MIX silages (p < 0.001). The concentrations of ammonia-N, lactate, and acetate were highest in LBR silage (p = 0.008; p < 0.001; p < 0.001). Propionate and butyrate concentrations were highest in CON silage (p = 0.004; p < 0.001). The LAB and yeast counts were higher in CON and LHO silages compare to LBR and MIX silages (p < 0.001). However, the mold did not detect in all treatments. Therefore, this study could conclude that L. brevis 100D8 and Leu. holzapfelii strain 5H4 can improve the digestibility and anti-fungal activity of high moisture rye silage.

본 연구에서는 수확 후 저장 기간에 따른 절화 장미의 수명 변화를 알아보았다. 절화장미 ‘Antique Curl’을 수확 직후 4℃ 암조건의 저장고에서 0일(무처리), 1일, 3일, 5일, 7일간 보존 용액 처리 후 습식 저장하였다. 저장이 끝난 절화는 24℃ 실 내 광환경으로 옮겨 절화 보존제 유무 조건에서 절화수명을 조사하였다. 그 결과, 절화수명은 저장기간 3일차까지는 20일 전후로 높았으나, 5일차 이후 유의적으로 감소했다. 절화 보 존제는 절화수명 연장에 효과적이지는 않았으나 절화의 꽃목 굽음 현상을 완화시켰다. 엽록소 형광(Fv/Fm)은 저장 기간과 관계없이 0.78~0.82 수준으로 나타났으며 저장기간에 의한 광 생리 기능저하는 확인되지 않았다. 결과적으로 절화장미 ‘Antique Curl’의 상업적 저장 기한은 최대 5일로 확인되었다.

Functional dyspepsia (FD) is a gastrointestinal disorder with diverse symptoms but no structural or organic manifestations. Benachio-F® (herein named ‘BF-1’) is an over-the-counter liquid digestive formulated with multiple herbal extracts, which has been reported to improve symptoms of FD. A total two experiments were conducted. First, we examined whether BF-1 can modulate the progression of FD through two experimental rat models. A total of three doses (0.3x, 1x, 3x of the human equivalent dose) were used. In the gastric emptying model, both 1x (standard) or 3x (3-fold-concentrated) BF-1 enhanced gastric emptying was compared with that of vehicle-treated animals. In a feeding inhibition model induced by acute restraint stress, treatment with 1x or 3x BF-1 led to a similar degree of restoration in food intake that was comparable to that of acotiamide-treated animals. Among the constituents of BF, fennel is known for its choleretic effect. Thus, we next investigated whether a novel BF-based formula (named ‘BF-2’) that contains an increased amount of fennel extract (3.5-fold over BF-1), has greater potency in increasing bile flow. BF-2 showed a superior choleretic effect compared to BF-1. Furthermore, the postprandial concentration of serum secretin was higher in animals pretreated with BF-2 than in those pretreated with BF-1, suggesting that the increased choleretic effect of BF-2 is related to secretin production. Our results demonstrate that BF-1 can modulate the pathophysiological mechanisms of FD by exerting prokinetic and stress-relieving effects, and that BF-2 has a better choleretic effect than BF-1.

Mesenchymal stem cells (MSCs) have been recognized as a therapeutic tool for various diseases due to its unique ability for tissue regeneration and immune regulation. However, poor survival during in vitro expansion and after being administrated in vivo limits its clinical uses. Accordingly, protocols for enhancing cell survivability is critical for establishing an efficient cell therapy is needed. CDDOMe is a synthetic C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, which is known to stimulate nuclear factor erythroid 2-related factor 2 (Nrf2)- antioxidant response element (ARE) pathway. Herein, report that CDDO-Me promoted the proliferation of MSCs and increased colony forming units (CFU) numbers. No alteration in differentiation into tri-lineage mesodermal cells was found after CDDO-Me treatment. We observed that CDDO-Me treatment reduced the cell death induced by oxidative stress, demonstrated by the augment in the expression of Nrf2-downstream genes. Lastly, CDDO-Me led to the nuclear translocation of NRF2. Our data indicate that CDDO-Me can enhance the functionality of MSCs by stimulating cell survival and increasing viability under oxidative stress.

The sensory stimulation of a cosmetic product has been deemed to be an ancillary aspect until a decade ago. That point of view has drastically changed on different levels in just a decade. Nowadays cosmetic formulators should unavoidably meet the needs of consumers who want sensory satisfaction, although they do not have much time for new product development. The selection of new products from candidate products largely depend on the panel of human sensory experts. As new product development cycle time decreases, the formulators wanted to find systematic tools that are required to filter candidate products into a short list. Traditional statistical analysis on most physical property tests for the products including tribology tests and rheology tests, do not give any sound foundation for filtering candidate products. In this paper, we suggest a deep learning-based analysis method to identify hand cream products by raw electric signals from tribological sliding test. We compare the result of the deep learning-based method using raw data as input with the results of several machine learning-based analysis methods using manually extracted features as input. Among them, ResNet that is a deep learning model proved to be the best method to identify hand cream used in the test. According to our search in the scientific reported papers, this is the first attempt for predicting test cosmetic product with only raw time-series friction data without any manual feature extraction. Automatic product identification capability without manually extracted features can be used to narrow down the list of the newly developed candidate products.

Continuous synthesis of high-crystalline carbon nanotubes (CNTs) is achieved by reconfiguring the injection part in the reactor that is used in the floating catalyst chemical vapor deposition (FC-CVD) process. The degree of gas mixing is divided into three cases by adjusting the configuration of the injection part: Case 1: most-delayed gas mixing (reference experiment), Case 2: earlier gas mixing than Case 1, Case 3: earliest gas mixing. The optimal synthesis condition is obtained using design of experiment (DOE) in the design of Case 1, and then is applied to the other cases to compare the synthesis results. In all cases, the experiments are performed by varying the timing of gas mixing while keeping the synthesis conditions constant. Production rate (Case 1: 0.63 mg/min, Case 2: 0.68 mg/min, Case 3: 1.29 mg/min) and carbon content (Case 1: 39.6 wt%, Case 2: 57.1 wt%, Case 3: 71.6 wt%) increase as the gas-mixing level increases. The amount of by-products decreases stepwise as the gas-mixing level increases. The IG/ID ratio increases by a factor of 7 from 10.3 (Case 1) to 71.7 (Case 3) as the gas-mixing level increases; a high ratio indicates high-crystalline CNTs. The radial breathing mode (RBM) peak of Raman spectrograph is the narrowest and sharpest in Case 3; this result suggests that the diameter of the synthesized CNTs is the most uniform in Case 3. This study demonstrates the importance of configuration of the injection part of the reactor for CNT synthesis using FC-CVD.

Human and material resource planning is one representative example of Operations Research. Resource planning is important not only in civilian settings but also in military ones. In the Air Force, flight scheduling is one of the primary issues that must be addressed by the personnel who are connected to flight missions. However, although the topic is of great importance, relatively few studies have attempted to resolve the problem on a scientific basis. Each flight squadron has its own scheduling officers who manually draw up the flight schedules each day. While mistakes may not occur while drafting schedules, officers may experience difficulties in systematically adjusting to them. To increase efficiency in this context, this study proposes a mathematical model based on a binary variable. This model automatically drafts flight schedules considering pilot’s mission efficiency. Furthermore, it also recommends that schedules be drawn up monthly and updated weekly, rather than being drafted from scratch each day. This will enable easier control when taking the various relevant factors into account. The model incorporates several parameters, such as matching of the main pilots and co-pilots, turn around time, availability of pilots and aircraft, monthly requirements of each flight mission, and maximum/minimum number of sorties that would be flown per week. The optimal solution to this model demonstrated an average improvement of nearly 47% compared with other feasible solutions.