KOREASCHOLAR

Skin plays important roles in protecting the internal organs from the chemical-biological risk factors and ultraviolet light. Exposure to the chemical and biological stimuli has a detrimental effect on skin's structure and physiological regulation. Therefore, much attention has been paid to natural products that show biological activities such as anti-oxidation, anti-aging and anti-bacterial activities. In this study, we investigated the skin-related biological activities of Oenothera lamarckiana aerial part extract. The extract contained 229.35 mg TAE (tannic acid equivalents)/g total polyphenolic compounds and the extract showed relative high antioxidant activity (SC50 value: 8.52 μg/mL). The IC50 value against tyrosinase and elastase were 307.94 and 181.51 μg/mL, respectively. This suggested that O. lamarckiana can be applied to whiten skin and slow the aging of skin. O. lamarckiana extract showed a growth inhibitory effect on Staphylococcu epidermidis (minimum inhibitory concentration: 250 μg/mL). Interestingly, O. lamarckiana extract showed no inhibitory effect on Pseudomonas aeruginosa on the paper disc assay. Yet the extract inhibited the growth of Pseudomonas aeruginosa on the broth dilution assay in a dose-dependent manners. Taken together, O. lamarckiana could have good potential for development as an additive in the cosmetic industry.

Abstract
I. 서 론
II. 연구 내용 및 방법
III. 결과 및 고찰
IV. 요약 및 결론
References

• 양지영(연세대학교 보건과학대학 임상병리학과) | Ji Yeong Yang (Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University)
• 김진우(세명대학교 바이오제약산업학부) | Jin Woo Kim (School of Industrial Bio-pharmaceutical Science, Semyung University)
• 이평재(세명대학교 바이오제약산업학부) | Pyeongjae Lee (School of Industrial Bio-pharmaceutical Science, Semyung University) Corresponding author