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한국 재래돼지의 산육형질에 대한 육종가와 후보유전자 다형성간의 연관성 분석 KCI 등재

Association of Polymorphism in Korean Native Pig with Breeding Values for Performance Traits and Candidate Genes

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동물자원연구 (Annals of Animal Resources Sciences)
강원대학교 동물자원공동연구소 (Institute of Animal Resources Kangwon National University)
초록

The relationship of several candidate genes polymorphisms with breeding values of economic traits were investigated in Korean Native Pigs. Record (2001-2006) of 546 Korean native pigs were obtained from National Institute of Animal Science, Korea having data on average daily gain (ADG), age at 70 kg (D70 kg) and backfat thickness (BF). The data's obtained were analyzed by the DF-REML (Derivative-Free Restricted Maximum Likelihood) program of Boldman using a single-trait animal model to analyse the genetic parameters. The analysis of restriction fragment length polymorphism (RFLP) was conducted on 68 Korean native pigs (KNP) using single nucleotide polymorphism (SNP). Different genotype frequencies of 5 candidate genes such as MC4R, PRKAG3, FABP3, ESR and PRLR3 were observed in KNP. Significant relationship of AA and AB genotype between MC4R polymorphic site and breeding value for average daily gain (ADG, p<0.05) was observed. PRKAG3 polymorphic sites were also found to be significantly related to breeding values for ADG, AA, AB genotype (p<0.05) and also, for Backfat thickness (BF), days to 70 kg and BB genotype (p<0.05). In conclusion, selection method would be more effective if it encompasses significant genotype for performance traits and that would further aid in the selection of seed stock in KNP.

목차
ABSTRACT   I. 서론   II. 재료및 방법    1. 공시재료    2. Genomic DNA 정제    3. DNA 증폭 및 RFLP    4. 육종가 추정 및 통계분석   III. 결과 및 고찰   IV. 요약   V. 인용문헌
저자
  • 김명직(국립축산과학원) | Myung-Jick Kim Corresponding Author
  • 조규호(국립축산과학원) | Kyu-Ho Cho
  • 권오섭(국립축산과학원) | O-Sub Kwon
  • 최봉환(국립축산과학원) | Bong-Hwan Choi
  • 김인철(국립축산과학원) | In-Chul Kim