In this study, we attempt to analyze biofilter"s removal efficiency for volatile organic compounds from paint factory. this experiment conducted in a pilot plant with microorganisms immobilized polyurethane foam. 7 main components (Toulene, MEK, MIBK, o-Xylene, m-Xylene, Butyl acetate, Ethyl benzene) emitted from factory ventilation opening were analyzed. During the test period, the biofilter treated VOCs in 5 seconds (EBCT) and pressure drop was less than 30 ㎜H₂O/m in media. Removal efficiencies of all components were between 80~90% in 10 days of operation and higher than 94% after 40 days. The result of this experiment shows that biofilter can be useful technology for VOCs removal in the paint industry.