Cholangiocarcinoma is a relatively rare neoplasm in animals and humans. A four-year-old, neutered male ferret presented with depression, anorexia, cachexia diarrhea, and icterus. Necropsy findings included ascites multiple white nodules on the surface of the liver, stomach and duodenum, gross enlargement of the bile duct and right atrium, hemorrhage of the gastric and duodena mucosa, and icterus of the mesenteric fat. Infiltrative well differentiated neoplastic biliary epithelial cells forming ducts and acini with a prominent collagenous stroma were observed on microscopic examination of neoplastic lesions within the liver, mesentery, and the serosa of the stomach and duodenum. This is a report on a rare case of obstructive jaundice due to cholangiocarcinoma in a ferret.

• Ho-Suk Lee(Department of Pathology, College of Veterinary Medicine, Kyungpook National University)
• Kyung-Ku Kang(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Chang-Woo Min(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Eun-Mi Lee(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Eun-Mi Lee(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Eun-Joo Lee(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Myeong-Mi Lee(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Sang-Hyeob Kim(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Soo-Eun Sung(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University)
• Kyu-Shik Jeong(Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Stem Cell Therapeutic Research Institute, Kyungpook National University) Corresponding Author