논문 상세보기
pp.302-306
예로구터 그 수액이 건강보조식품으로 사용되어온 고로쇠나무의 줄기를 대상으로 항산화 활성을 가지는 성분을 찾기위하여 실험에 착수하였으며, 그 MeOH추출물의 ETOAc분획을 대상으로 Column chromatography를 실시하여 scopoletin, isoscopoletin, (-) -epicatechin등 3종의 화합물을 분리하고 항산화 활성을 측정하였다. 이중 scopoletin과 isoscopoletin은 BHA나 α-tocopherol보다 활성이 약하였으나 (RC50 : 120, 110 mug), (-)-epicatechin의 항산화활성 (RC50 : 7.5 mug)은 BHA나 α-tocopherol보다 뚜렷하게 높았다.
One flavan 3-ol derivative was isolated from the stem of Acer mono Max, along with two known coumarins. On the basis of spectroscopic evidence, the structures of these compounds were established as (-) - epicatechin, scopoletin and isoscopoletin. Antioxidative activity of (-) - epicatechin was examined by the DPPH free radical scavenging method. Antioxidative activity of (-) - epicatechin (RC50 : 7.5 mug) was more greater than those of α-tocopherol (RC50 : 12 mug) and BHA (RC50 : 14 mug).
