광순환 에너지를 갖는 Halobacterium Halobium에서 마취제의 혼합에 따른 Membrane의 부피 변화

김기준; 성기천; 이후설

논문 상세보기

광순환 에너지를 갖는 Halobacterium Halobium에서 마취제의 혼합에 따른 Membrane의 부피 변화 KCI 등재

Volume Change of Membrane Mixed with Various Anesthetics in Halobacterium Halobium with Photo-Cyclic Energy

김기준, 성기천, 이후설

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한국응용과학기술학회지 (The Korean Society of Applied Science and Technology)

Vol.13 No.3 (1996.11)
pp.119-125

한국응용과학기술학회(구 한국유화학회) (The Korean Society of Applied Science and Technology (KSAST))

초록

The excess volumes of mixing of benzyl alcohol, ethyl alcohol, halothane, and procaine in vesicle and suspensions of several lipids have been determined at 25℃ using a excess volume dilatometer. The potency of general anesthetics has long been known to be correlated with lipid solubility. Denaturations of the bacteriorhodopsin, which is a sole membrane protein in the purple membrane of Halobacteriun Halobium, were studied by UV/Vis absorption changes. The excess volumes of mixing of benzyl alcohol and procaine in egg lecithin were all found to be negative and this result was confirmed as Miller's supposition.

저자

김기준 | Kim, Ki-Jun
성기천 | Sung, Ki-Chun
이후설 | Lee, Hoo-Seol

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