Lilies are of great economic important floweringplant that belongs to the genus Lilium can be grown underdiverse climatic conditions. During the last decade the lilyhas gained popularity worldwide among cut flowers and pot-ted flowering plants. Seeing the great recognition of lilies ininternational flower trade, several breeding approacheshave been adopted on different Lilium sections/groups andmore than 10,000 lily cultivars have been bred. Innovativebreeding strategies and advancement in molecular and bio-technology techniques have made the assortment of liliesdramatically. Different DNA marker approaches have greatpotential to increase the precision and efficiency of conven-tional lily breeding via marker-assisted selection (MAS) anddifferent breeders used it for Lilium crop improvement. Inthis review, different approaches and techniques that lilybreeders have employed to develop novel cultivars are dis-cussed. It is imperative to recognize that there must be anenhanced integration and synchronization in different lilyobjective oriented breeding programs, so that current issues,barriers etc. can be well identified with their appropriatesolutions.