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Antioxidant and Tyrosinase Inhibitory Activity of Hypsizigus marmoreus Extracts

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  • URLhttps://db.koreascholar.com/Article/Detail/277141
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한국버섯학회 (The Korean Society of Mushroom Science)
초록

The mushrooms have been used as traditional medicines and food resources in many countries. The objective of this study was to determine antioxidant compounds and to evoluate tyrosinase inhibitory activity of extracts from Hypsizigus marmoreus. The pileus and stipe of Hypsizigus marmoreus were extracted with methanol and water, separately. The methanol extract of Hypsizigus marmoreus were fractioned by hexane, chloroform, ethylacetate and buthanol. The concentrations of total polyphenolics and flavonoids in methanol extracts were investigated by colorimetric methods. The concentrations of total polyphenolics and flavonoids in methanol extract of the pileus was higher than methanol extract of the stipe. The DPPH redical scavenging activity of the pileus extract was also higher than stipe extract in methanol extract. The IC50 of DPPH redical scavenging activity of the pileus and stipe in methanol extract were 18 mg/ml and 1 10 mg/ml, respectively. The IC50 of tyrosinase inhibitory activity of the pileus and stipe in methanol extract were 500 mg/ml and 1,000 mg/ml in methanol extract. These results suggest that Hypsizigus marmoreus can be potentially used as a source of natural antioxidant agent in the cosmetic industry as well as the food, pharmaceutical and medicinal industry.

저자
  • Soo Chul Kim(Dept. of Pharmaceutical Engineering, Gyeongnam National University of Science and Technology, Jinju 660-758, Korea)
  • Han Min Ryu( Dept. of Pharmaceutical Engineering, Gyeongnam National University of Science and Technology, Jinju 660-758, Korea) | Han Min Ryu
  • Sung Mi Jung( Dept. of Pharmaceutical Engineering, Gyeongnam National University of Science and Technology, Jinju 660-758, Korea) | Sung Mi Jung
  • Young Hyun Lee( Dept. of Pharmaceutical Engineering, Gyeongnam National University of Science and Technology, Jinju 660-758, Korea) | Young Hyun Lee
  • Jong Ok Kim( Namkyung Co., Ltd, Cheongdo-gun, Gyeongbuk 714-841, Korea) | Jong Ok Kim
  • Soo Jeong Cho( Dept. of Pharmaceutical Engineering, Gyeongnam National University of Science and Technology, Jinju 660-758, Korea) | Soo Jeong Cho