FDI in China begins in 1979 with China's reform and opening-up, which has brought China a great progress in the economic development up to now. For the sake of attracting FDI to China, Chinese government has built several special economic zones around coastal areas and the scale of FDI in China has been greeting its prosperous time since China's entry into WTO in 2001. In 2002, China firstly surpassed the USA and ranked as the first in the world with 52.7 billion dollars of annual FDI. More recently, the actual FDI in 2012 in China was 111.7 billion dollars, making a great contribution to China's economic development. With the guidance of government, most of the FDI focused on the coastal areas in east of China during the past 30 years. However, in order to reduce the regional differences, narrow the wealth gap, the FDI in major eastern cities and coastal areas has been gradually transferred to the central and western regions of China. This study makes a positive analysis on the determining factors of FDI site selection in China, according to the data provided by 29 provinces in the past 28 years. This analysis focuses on all the east, central and west regions of China. The results of regression analysis indicate that: 1. In a national scope, the FDI in China is proportional to the GRDP and export, but inversely proportional to salaries and students percentage.2. In the eastern, central and western local scope, the FDI in this three regions is all proportional to the GRDP and the percentage of secondary industry, but inversely proportional to salaries and students percentage. Additionally, the FDI is proportional to the export in east of China, while that is not obvious in central and western regions.3. The study on the three-region interactions shows that the FDI in three regions are proportional and the closer the locations are, the deeper the influence is. Therefore, the conclusion is that relationship of the three regions is not competitive but mutually promotive.