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Ticks and Severe Fever with Thrombocytopenia Syndrome (SFTS)
- 언어ENG
- URLhttps://db.koreascholar.com/Article/Detail/288305
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging disease, causing high fever, thromobocytopenia, leukopenia, gastrointestinal simptoms (vomiting, diarrhea), hemorrhage and multiorgan dysfunction. It was known that Haemaphysalis longicornis (H. longicornis), a major tick in Korea, is the principal vector for severe fever with thrombocytopenia syndrome virus (SFTSV).
Firstly, to investigate the existence and prevalence of SFTSV in the country, we collected the ticks in 9 provinces in South Korea and detected SFTSV from H. longicornis ticks from 2011 to 2012. And we also investigated SFTSV infection in ticks collected from healthy humans without SFTS symptom and their residential areas. From the former study, we collected 13,053 ticks, and H. longicornis (90.8%, 11,856/13,053) was the most abundant among them. The minimum infection rate (MIR) of SFTSV in H. longicornis was 0.5% (59 pools). From the later study, totally 422 ticks of 8 species were collected from humans and at their neighborhood throughout the nation from May to October, 2013 and SFTSVs were detected from 12 pools (5.7% MIR) by RT-PCR. Finally, we diagnosed 35 patients by detecting SFTSV gene with their sera, and isolated 26 SFTSVs among them in 2013.
These findings indicate that SFTSVs are prevalent and SFTS is probably endemic in Korea.
