In this article, we reported the characterization of mechanical properties for several scaffolds fabricated by different techniques: bio-plotter technique and WNM(wire-network molding). Firstly, we constructed numerical models for ABAQUS: a commercial computational analyzing program. Using ABAQUS, effective compressive are calculated and compared with the experimental results from UTM tests. The results show that the stiffness of the scaffold fabricated by WNM is stronger than that by bio-plotter technique.