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Toxic Hepatitis by Repetitive Administration of Albendazole in a Short Time

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

Albendazole is the most commonly used medication worldwide for parasitic infestation. Albendazole may induce side effects such as nausea, vomiting, abdominal discomfort, and headache, however hepatotoxicity is rare. A 37-year old woman was admitted to the hospital due to headache. Her child had been repeatedly infected with enterobius vermicularis, therefore she took albendazole three times for prophylactic purposes. The patient was diagnosed with hepatotoxicity induced by Albendazole based on a history of drug use; clinical symptoms and laboratory tests improved after ceasing drug administration, with a Roussel Uclaf Causality Assessment Method (RUCAM) score of 12.

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저자
  • 신홍식(전주예수병원 내과) | Hong Shik Shin
  • 김병관(전주예수병원 내과) | Byeong Gwan Kim
  • 조아영(전주예수병원 내과) | A Young Cho
  • 이성희(전주예수병원 내과) | Seong Hee Lee
  • 윤소희(전주예수병원 내과) | So Hee Yun
  • 조용근(전주예수병원 내과) | Yong Keun Cho Corresponding author
  • 이광민(전주예수병원 병리과) | Kwang Min Lee
  • 유설봉(전주예수병원 병리과) | Seol Bong Yoo