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Current trends and future prospects in insect genomics

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/313077
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한국응용곤충학회 (Korean Society Of Applied Entomology)
초록

In recent years, high-throughput next-generation sequencing (NGS) techniques have provided fascinating opportunities to understand the biology of non-model organisms, especially insect species. The decrease in sequencing costs and extensive sequencing services from NGS providers has brought many entomologists to be involved in genome sequencing. However, poor planning can lead to extremely fragmented genome assemblies which prevents high quality gene annotation and other desired analyses. Insect genomes can be problematic to assemble, due to combinations of high polymorphism, inability to breed for genome homozygosity, and small physical sizes limiting the quantity of DNA able to be isolated from a single individual. Given to the rapid development of host resistance to multiple classes of insecticides, it is indispensable to study the comprehensive genomic information of insects. Recent advances in sequencing technology and assembly strategies can able to fetch breakthroughs in deciphering the genetic information of insects. Here, we present the cost effective high throughput genome sequencing and assembly strategies for insect species in respects to taxonomy, evolutionary history, immune response, drug development, insect host-virus interactions and pest management etc.

저자
  • Hyung Wook Kwon(Division of Life Sciences, College of Life Science and Bioengineering, Incheon National University)
  • Seungil Yoo(TheragenEtex Bio Institute)
  • Sathiyamoorthy Subramaniyam(TheragenEtex Bio Institute)
  • Seong-Eui Hong(TheragenEtex Bio Institute)
  • Kesavan Markkandan(TheragenEtex Bio Institute)
  • Junhyung Park(TheragenEtex Bio Institute)