This study was performed to investigate the effects of Acer tegmentosum Maxim. extract (ATE) on non-alcoholic fatty liver in Sprague Dawley (SD) rats. During oral administration of ATE, non-alcoholic fatty liver was induced by treatment with DL-ethionine. The lipid, total cholesterol (T-CHO) and malondialdehyde (MDA) in the liver tissue of ATE-fed rats showed lower levels, as compared to ATE-unfed rats. In ATE-fed rats, the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and γ-glutamyl transferase (GGT) were lower than the case of ATE-unfed rats. Oil red staining of the liver showed that the lipid deposits were decreased by feeding ATE. These results strongly indicated that ATE has positive effects of protection against non-alcoholic fatty liver formation.

서 론
 재료 및 방법
  1. 산겨릅나무 추출물 제조
  2. 시험동물
  3. 간지질 분석
  4. 혈액 생화학 검사
  5. 간 조직 중 peroxidase 함량 측정
  6. 간 조직내 지방 염색
  7. 통계분석
 결과 및 고찰
  1. 비알콜성 지방간 동물 모델의 체중 변화에 대한 연구
  2. 산겨릅추출물의비알콜성지방간간지질억제효과연구
  3. 산겨릅나무 추출물의 혈액 내 생화학 지표 분석
  4. 산겨릅나무 추출물로 인한 조직 변화 관찰
 요약 및 결론
 References

• 서윤희(충북대학교 생물학과) | Yoonhee Seo
• 이상화(서원대학교 친환경바이오소재 및 식품센터) | Sang-Hwa Lee
• 황형서(세명대학교 한방바이오융합과학부) | Hyung Seo Hwang Co-corresponding author
• 최수영(충북대학교 생물학과) | Soo Young Choe Co-corresponding author