Recently, Pharmaceutical Logistics Center in the introduction of automated equipment and systems for the efficiency of logistics is very important. However, the base of a distributed logistics, shipment data analysis and process improvement and automation, if not considered as an automated logistics center can not function well in many cases. To do this, we first classify the specific background factors in pharmaceutical environment factor and then develop the automation system model to analyze the factors that affect the pharmaceutical distribution center. We also develop a efficiency of Logistics Center thorough DPS(Digital Picking System), DPC(Digital Picking Cart System), Sorter such as factory automation equipment by improving the process and data analysis.