Background : Ginseng, an important traditional medicinal plant still used in rats with bone fractures or dislocation to promote connective tissue repair and to reduce inflammantion. We investigated the effect of ginseng on the proliferation rate of rat bone. Methods and Results : We investigated the effect of ginseng extracts on blood biochemical parameters, bone density and bone inorganic components etc. and data were analyzed by one-way ANOVA. In the results of our study, the level of albumin and HDL, Ca, P, Mg, and estradiol in blood, and the content of Ca, P, ash in femur were significantly increased in ginseng treated group than in OVX group, and the level of ALP, AST, ALT, blood glucose, total cholesterol, triglyceride, LDL, creatinine, osteocalcin, and N-terminal telopeptide were significantly decreased in red ginseng treated group than in OVX group (p < 0.01). Conclusion : From these results, we knew that within the normal level, ginseng extracts improved liver and kidney function, component of glucose and lipid in blood, bone densith, bone ash and inorganic components in femur, and index related with bone metabolism.

• Young Ock Kim(Department of Herbal Corp Reasearch, RDA) | 김영옥
• Kyung Hun Park(Department of Herbal Corp Reasearch, RDA) | 박경훈
• Yu Su Shin(Department of Herbal Corp Reasearch, RDA) | 신유수
• Ji Yeon Lee(Department of Industrial Plant Science and Technology, Chungbuk National University) | 이지연
• Young Sup Ahn(Department of Herbal Corp Reasearch, RDA) | 안영섭
• Chun Geon Park(Department of Herbal Corp Reasearch, RDA) | 박춘근 Corresponding author