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스트레스 동물모델에서 행동과 생리적 활동에 대한 쥐오줌풀의 효과
Effects of Valeriana fauriei on Behavioral and Physiological Outcomes in an Animal Model of Stress
- 언어ENG
- URLhttps://db.koreascholar.com/Article/Detail/326649
Background : Our animal model of stress contained two components: (1) acute trauma, immobilization of rats in close proximity to a cat twice in 10 days, and (2) chronic social instability, 31 days of randomized housing of cage cohorts. Here we tested the hypothesis that daily social stimulation would block the development of the stress. Methods and Results : Beginning 24 h after the first cat exposure, adult male rats were given our established stress model, alone or in conjunction with daily social stimulation, in which all rats within a group interacted in a large apparatus for 2 h each day for the final 30 days. All behavioral, for example, anxiety, memory, startle testing, and physiological assessments, for example, body growth, organ weights, and corticosterone levels, took place following completion of the psychosocial stress period. Conclusion : From the above study, V. fauriei possess significant anti-stress properties and can be used for the treatment of stress-induced disorders.
