This study was conducted to evaluate the hangover relieving effect of algae and plant complex extract. The complex extract showed 1,1-diphenyl-2-picrylhydrazyl radical scavenging effect in a concentration-dependent manner and high antioxidant capacity (59.48%) when administered at 120 μg/mL. In addition, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activities were increased according to the concentration of the complex extract. A locomotor activity test with an alcohol-complex extract mouse group showed improved motor activities over that of the alcohol-water group at 120 min post-administration. Blood was harvested from each mouse at 120 min post-administration then concentrations of alcohol and aldehyde were measured. The alcohol-extract treated group showed significantly lower (p<0.0001) alcohol (33.48 ± 0.59 μg/mL) and aldehyde (1.54 ± 0.13 μg/mL) concentrations than the alcohol-water treated group. These results suggest that the hangover relieving effects of complex extract results in increased motor activity of mice, which reduces the alcohol and aldehyde concentration in the blood.

Abstract
 서 론
 재료 및 방법
  해조류 및 식물 복합추출물 시료의 준비
  실험동물 및 사육조건
  항산화 효과 측정
  ADH/ALDH 활성 측정
  혈중 acetaldehyde /alcohol 정량
  Locomotor activity test
  통계분석
 결과 및 고찰
  항산화 효과 측정
  ADH/ALDH 활성 측정
  Locomotor activity test
  혈중 aldehyde 및 alcohol 정량
 요 약
 감사의 글
 References

• 손명수((주)비케이바이오, BK bio Co., Ltd.) | Myung-Soo Shon
• 문혜희(제주대학교 수의과학대학 수의학과, College of Veterinary Medicine, Jeju National University) | Hae Hee Moon
• 한창훈(제주대학교 수의과학대학 수의학과, College of Veterinary Medicine, Jeju National University) | Chang-Hoon Han
• 최혁준((주)비케이바이오, BK bio Co., Ltd.) | Hyuk-Joon Choi
• 한복경((주)비케이바이오, BK bio Co., Ltd.) | Bok Kyung Han Corresponding author