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Encapsulation of curcumin into starch-based microparticles during self-association for short glucan chain
Starch is an abundant, renewable, and low cost material that has been extensively studied for its role in crystallization. Herein, we developed a facile and green approach to produce the starch-based microparticles (SMPs) that could encapsulate curcumin during the self-association of short glucan chain obtained from waxy maize starch. Scanning electron microscopy (SEM) analysis indicated that the diameters of curcumin-loaded SMPs were ranged from 1.5 μm to 3 μm. The characteristics of the curcumin-loaded SMPs were evaluated via Raman spectroscopy, confocal microscopy, UV spectrophotometer, and X-ray diffraction (XRD). The results showed that the suspended curcumin was encapsulated in SMPs in amorphous form with a encapsulating efficiency of about 96.36%. Photostability test confirmed that curcumin that is loaded inside SMPs was effectively protected against the photodegradation. Curcumin-loaded SMPs can be used not only in food industry for extending the shelf life of curcumin, but also in pharmaceutical industry to design effective carrier for oral delivery.
