The purpose of this study is to examine the exposure risk of thermal paper ingredients by analyzing skin permeation using an in vitro Franz cell. Thermal printer papers are usually used for receipt papers, and the skin of shop assistant is continuously exposed to hazardous ingredients of thermal papers. The skin permeation risk of thermal paper ingredients, including bisphenol A and toluene, was determined using an in vitro Franz diffusion cell method using hairless mouse full skin and human cadaver epidermis. Bisphenol A, a major component in each thermal paper, showed moderate skin penetration. Most skin absorption rates were similar in both hairless mouse full skin and human cadaver epidermis. The possible risk of exposure to toxic substances in thermal paper was confirmed from this study. These is results are expected to contribute to establishment of management regulations for thermal papers.

Abstract
 서 론
 재료 및 방법
  시험 물질 및 분석기기
  피부 준비
  In vitro 피부흡수 실험
  물질의 피부흡수 결과 분석
 결 과
  감열지 제품 내 유해성분의 투과속도 및 투과계수
  피부 내 유해물질 잔류량 분석
 고 찰
 REFERENCES

• Kyo-Hyun Park(Department of Public Health, College of Natural Sciences, Keimyung University)
• Se-Hoon Jung(Department of Public Health, College of Natural Sciences, Keimyung University)
• Ho-Sang Shin(Department of Environmental Education, College of Education, Kongju National University)
• Seong-Eun Lee(Department of Beauty Coordination, Keimyung College University)
• Kiyoung Lee(Department of Environmental Health and Institute of Health and Environment, Graduate School of Public Health, Seoul National University)
• Bae-Hwan Kim(Department of Public Health, College of Natural Sciences, Keimyung University) Corresponding Author