The effect of inclination angle and attack angle on heat transfer enhancement of trapezoidal vortex generator was numerically investigated. The commercial package STAR-CCM+ was utilized to analyze the heat transfer and flow characteristics with various inclination and attack angle of vortex generator. The result shows that the optimum inclination angles are α =30°~40° in terms of the heat transfer and pressure drop. At more than 40° of inclination angle, the transverse vortex is dominant, so that the pressure drop is severe and the heat transfer is reduced. As the attack angle is increased, the transverse vortex is reduced, so that the pressure drop is improved. The optimum attack angle is β =30° because the heat transfer performance is maintained. However, more than 30° of attack angle, the heat transfer is decreasing.