Vortex Generators are used in heat exchanger to enhance the heat transfer of air side. 3-D numerical analysis is performed on heat transfer characteristics of a channel with trapezoidal vortex generator. We investigate the effects of vortex generators with two different inclined angles to flow direction which are forward and backward vortex generators. The thermal hydraulic performance such as Nu and pressure drop, is compared quantitatively. The results show that vortex generator enhances the heat transfer by developing boundary layers and secondary flow in the downstream. The downwash flow region corresponds to the maximum Nu, while the upwash flow region corresponds to Nu minimum. In the view of the heat transfer characteristics, FVG is better than BVG. However, when flow is turbulent as Re increases, the pressure drop for FVG is higher than that for BVG.