As indoor activities continue to increase, the importance of indoor air is emphasized. Moreover, children's activities are emphasized as being vulnerable. In this study, vocal organic compounds (VOCs) and CO2 in the indoor air were analyzed among children aged 4 to 7 years attending day care centers in Seoul. In the case of VOCs, the average concentration measured during a period of 24 hours in an asthmatic home was 143.9 (μg/m3). The average concentration measured during a period of 24 hours in the asthma and rhinitis home was 146.7 (μg/m3). In CO2, the average concentration measured during a period of 24 hours in the asthmatic home was 665.9 (ppm). The average concentration measured during a period of 24 hours in the asthma and rhinitis home was 695.9 (ppm). In this study, asthma symptoms increased as the concentration of indoor pollutants increased. Exposure of VOCs (μg/ m3) and CO2 (ppm) among environmental factors shows that respiratory symptoms such as asthma can be induced.