In this study, the structural stability of an align unit was studied to investigate the deformation and vibration characteristics of the upper and lower modules of the align unit during LCD panel transfer. The align unit consists of upper module and lower module. SolidWorks Simulation was used to analyze the structure, fatigue, and modes, to understand the deformation and vibration of the stiffness of the align unit. Because of the upper eccentric structure of the align unit, the main strain was large at the contact of the upper and lower modules and at the bottom of the support, and more pronounced at it’s front. The stress was large in the front support of the upper and lower modules, and the displacement was observed in the front of the upper module. The minimum life cycle that indicates the structural integrity of the align unit has exceeded its usable number. Also, the increase in natural frequency of the align unit gradually slowed down, as the vibration mode increased.