목적 : 뇌졸중 후 연하장애 중재에 포함된 임상가의 조기 접근을 위해 신경근전기자극(Neuromuscular Electronic Stimulation; NMES)와 비 침습성 뇌자극(Non-Invasive Brain Stimulation; NIBS)를 적용한 무작위 대조실험(Randomized Controlled Trials; RCTs) 연구의 메타분석을 통해 구체적인 효과와 방안을 제시하고자 한다.
연구방법 : Pubmed, CINAHL(EBSCOhost), Psycinfo, 한국학술정보원(Korean Studies Information Service System; KISS), 학술연구정보서비스(Research Information Sharing Service; RISS)를 통하 여 2008년부터 2019년까지의 논문을 검색하였다. 주요 용어는 “stroke OR CVA OR cerebrocascular accident OR vascular accident” AND “dysphagia OR swallowing disorder OR deglutition disorder” AND “tDCS OR transcranial direct current stimulation OR rTMS OR repetitive transcranial magnetic stimulation OR NMES OR neuromuscular electronic stimulation” AND “RCT OR randomized control trial”, “뇌졸중” 그리고 “연하장애 또는 삼킴곤란” 그리고 “경두개 자기자극 또는 경두개 직류자극 또는 신경근 전기자극” 그리고 “무작위대조실험”을 사용하였다. 포함기준과 배제기준을 적용하여 총 11개의 연구가 분석 대상으로 사용되었다.
결과 : 경두개 직류자극(Transcranial Direct Current Stimulation; tDCS)의 전기자극 강도는 1mA, 경 두개 자기자극(Repetitive Transcranial Magnetic Stimulation; rTMS)의 전기자극 강도는 3~5Hz, 신 경근 전기자극(Neuromuscular Electronic Stimulation; NMES)의 전기자극 강도는 8~15mA로 다양했으며, tDCS와 rTMS는 큰 효과크기, NMES는 중간 효과크기로 나타났다.
결론 : 본 연구는 메타분석을 통해 3가지 치료에 대한 효과를 확인하고 환자 특성과 중재 방향에 따라 다양한 결과를 확인할 수 있었다. 3가지 치료는 국내 뇌졸중 후 연하장애 회복에 효과가 있으며 안전하다고 판단한다. 향후 연하장애 회복을 이끄는 다양한 요인에 대한 명확한 연구가 활발히 이루어져야 할 것이다.

Objective: Randomized controlled trials (RCTs) using neuromuscular electronic stimulation (NMES) and non-invasive brain stimulation (NIBS) were applied for early access to clinicians included in a post-stroke swallowing intervention. A meta-analysis of the research will provide concrete effects and suggestions for improvement.
Methods: We searched articles from 2008 to 2019 published in Pubmed, CINAHL (EBSCOhost), Psycinfo, Korean Studies Information Service System (KISS), and the Research Information Sharing Service (RISS). The main key words are “stroke OR CVA OR cerebrocascular accident OR vascular accident” AND “dysphagia OR swallowing disorder OR deglutition disorder” AND “tDCS OR transcranial direct current stimulation OR rTMS OR repetitive transcranial magnetic stimulation OR NMES OR neuromuscular electronic stimulation” AND “RCT OR randomized control trial,” “뇌졸중” AND “연하장애,” AND “경두기 자기자극 OR 경두개 직류자극 OR 신경근전기자극” AND “무작위대 조실험.” The inclusion and exclusion criteria were applied to a total of 11 studies.
Results: The electrical stimulation intensity of transcranial direct current stimulation (tDCS) was 1 mA, the electrical stimulation intensity of repetitive transcranial magnetic stimulation (rTMS) was 3-5 Hz, the neuromuscular electrical stimulation (NMES) varied from 8 to 15 mA, tDCS and rTMS showed large effect sizes, and NMES demonstrated a medium effect size.
Conclusion: This study confirmed the effects of three treatments through a meta-analysis and confirmed the various results according to the patients' characteristics and mediation direction. However, three treatments are deemed effective for the recovery of swallowing disorder after a stroke in Korea and are considered safe. In addition, it is necessary to study various factors leading to a recovery of a swallowing disorder.

국문초록
Ⅰ. 서 론
Ⅱ. 연구 방법
    1. 연구 설계 및 문헌검색 전략
    2. 문헌 선정기준
    3. 질적 분석방법
    4. 계량적 메타분석방법
Ⅲ. 연구 결과
    1. 분석 대상 연구의 선정 과정
    2. 일반적 특성 및 질적 메타분석 결과
    3. 계량적 메타분석 결과
Ⅳ. 고 찰
Ⅴ. 결 론
References
Abstract

• 신치환(대한작업치료사협회) | Shin Chi-Hwan (Korean Association of Occupational Therapists, Editorial Assistant)
• 차선아(동대구아동발달센터) | Cha Sun-A (Dongdaegu Kids Development Center, Occupational Therapist) Corresponding author