In this study, by using a system analysis program(Fluid Flow), the correlation between the location where cladding damage occurs frequently inside the power plant seawater pipe and flow characteristics is analyzed, and the root cause and improvement plan are reviewed. As a result, it was confirmed that a high flow velocity occurred in the backwash piping(7.64m/s) and the front and rear ends of the flow control valve(5.93m/s). In addition, it was confirmed that cavitation occurs when the seawater level decreases below the saturated water vapor pressure at the rear end of the orifice. These areas are locations where the internal cladding damage occurs frequently in power plants, and the main cause of damage is considered to be excessive flow velocity and cavitation in the pipe. In order to solve this problem, improvement method such as installation of backwash pipe orifices, change of pipe shape at the front and rear end of flow control valve, and change of orifice type were derived.